The Reds can move 11 points clear of City at the top of the table if they beat Pep Guardiola's team in the 4pm GMT kick-off.

Here are 13 statistics to know about the clash…

In the Premier League, Liverpool have won 21 of the 54 previous meetings, with 21 draws and 12 losses. At Anfield, they have won 17, drawn eight and lost only two.

However, the Reds have won only one of the last nine home and away league encounters, when Mohamed Salah scored in a 1-0 home victory in October 2022.

Liverpool have failed to score in only one of the last 30 league clashes at Anfield, in a goalless draw in October 2018. That is the only 0-0 stalemate in the last 28 league meetings between the sides.

Both teams have scored in 10 of the last 11 meetings across all competitions. The only clean sheet in that time was by the Reds in that 1-0 league win in October 2022.

Caoimhin Kelleher's stop from Real Madrid's Kylian Mbappe on Wednesday saw him become the first Reds goalkeeper since Augustus Beeby in December 1909 to save a penalty in successive matches.

City have missed three of their last four penalties against Liverpool: Riyad Mahrez (2018) and Ilkay Gundogan (2021) at Anfield and Kevin De Bruyne (2020) at Etihad Stadium.

Arne Slot's team have kept six clean sheets in 12 Premier League outings this season, the most of any top-flight club going into this round of fixtures.

The Reds have scored in 63 of their last 67 home league games.

Salah has made more appearances for the club against City (20) than any other team and has scored in five of his seven league appearances against them at Anfield. Only Ian Rush (15) has scored more goals for Liverpool versus City than Salah's 11.

At Anfield, Salah has scored in each of Liverpool's last five Premier League outings, netting six goals in that sequence.

The Reds' last fixture on December 1 saw them win the Merseyside derby 4-1 at Goodison Park in 2021.

Slot's side have won all 14 matches so far this season when they have scored the game's first goal.

The last Liverpool player to score more than once in a game against City was Andy Carroll in a 3-0 Anfield victory in April 2011.